Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 agonist (GLP). Dual GIP/GLP-1 agonists gained increasing attention as new agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor agonists in preclinical and clinical trials.
The protein sequence of Tirzepatide was based on the sequence of endogenous GIP, and its pharmacological action on GLP-1 receptors is comparable to endogenous GIP. It has a role as a glucagon-like peptide-1 receptor agonist, an anti-obesity agent, a hypoglycemic agent, a gastric inhibitory polypeptide receptor agonist, and an incretin mimetic.
Sample Dosing Schedule:
Serious Warning: Please dose this product responsibly. If you’re new to the product, or haven’t taken it in some time, you need to start small. Skipping to a high dose too soon will cause incredibly unpleasant & long-lasting side effects. Most users will not need to progress through to the highest dosage level to achieve substantial results.
| Week 1 through 4 | 2.5mg per week | Initial onboarding dose |
| Week 5 through 8 | 5mg per week | Dose Escalation (if needed) |
| Week 9 through 12 | 7.5mg per week | Dose Escalation (if needed) |
| Week 13 through 16 | 10mg per week | Dose Escalation (if needed) |
| Week 17 through 20 | 12.5mg per week | Dose Escalation (if needed) |
| Week 21+ | 15mg per week | Maximum indicated dose |
*Sterile/ bacteriostatic water sold separately
